Categories | Sarms Raw Powder |
---|---|
Brand Name: | TINGYI |
Model Number: | 135463-81-9 |
Certification: | GMP , ISO 9001:2008 |
Place of Origin: | CHINA |
MOQ: | Negotiation |
Price: | Contact Us |
Payment Terms: | Bank Transfer - Bitcoin - Western Union - MoneyGram |
Supply Ability: | 100 KG/Month |
Delivery Time: | Within 7 Working Days |
Packaging Details: | Stealth And Discreet Packaging |
Product Name: | Coluracetam |
Other Name: | MKC 231 |
CAS: | 135463-81-9 |
Appearance: | White Powder |
Usage: | Nootropic Powder |
Shipping Method: | EMS, HKEMS, FEDEX, DHL, UPS, Aramex, ETC |
High Purity MKC 231 Sarms Coluracetam CAS 135463-81-9 Nootropic Powder With Factory Price
CAS:135463-81-9
MF:C19H23N3O3
MW:341.4
Synonyms:COLURACETAM;N-(2,3-Dimethyl-5,6,7,8-tetrahydrofuro[2,3-b]quinolin-4-yl)-2-(2-oxopyrrolidin-1-yl)acetamide;1-Pyrrolidineacetamide,2-oxo-N-(5,6,7,8-tetrahydro-2,3-dimethylfuro[2,3-b]quinolin-4-yl)-;Coluracetam, MKC-231;1-[N-(2,3-DiMethyl-5,6,7,8-tetrahydrofuro[2,3-b]quinolin-4-yl)carbaMoylMethyl]pyrrolidin-2-one;BCI-540;Coluracetam, >=99%;2-oxo-N-(5,6,7,8-tetrahydro-2,3-dimethyl-furo[2,3-b]quinolin-4-yl)-1-pyrrolidineacetamide
What is Nootropics
Nootropics are supplements, drugs, or functional foods, that
enhance cognitive functions such as intelligence, memory, and
focus.
Nootropics, colloquially referred to as "smart drugs," have seen an
influx of interest over the last several years as people search for
ways to maximize their brain's potential.
What is Coluracetam
(1)Coluracetam, as known as MKC-231 has been classed as a nootropic
agent. It's known to enhance cognitive effects, based on the ways
in which it influences choline uptake. Originally developed to
treat Alzheimer's disease, Coluracetam was found to be more
effective as a nootropic and is purely marketed as a cognitive
enhancer.
(2)It is one of the newer racetam nootropics to reach the market. Since Coluracetam enhances levels of choline in the brain and body, it increases the production of acetylcholine. Without acetylcholine, we wouldn't be able to remember the simplest of facts or move our muscles. It's been reported that Coluracetam not only increases acetylcholine levels but also speeds up its flow.
Benefits and effects
(1)Coluracetam offers many benefits, however, the most exciting is
its ability to improve long-term memory within memory-impaired
individuals. Humans have tested Coluracetam, but the majority of
testing has taken place with animals. When tested on rats using a
commonly used maze test, memory improved. The effects continued,
improving memory after this supplement had left their system. This
shows that Coluracetam may have potentially long-term effects.
(2)As mentioned, when tested within the Phase 2A trails,
Coluracetam showed that it was effective in treating both
depression and anxiety. Some patients had not experienced any
positive effects in the past by taking anti-depressants, yet
experienced the benefits associated with Coluracetam. While
assessing depression levels, 36 percent of participants experienced
significant improvements.
(3)Many other users also expressed the way in which this supplement
creates feelings of contentment and deep peace. When used with
other racetams, Coluracetam produces nootropic-like effects. Not
only is memory improved, but decision making, along with a number
of other cognitive effects increase. This has been shown through a
number of studies, reporting that Coluracetam enhances the overall
speed of cognition and concentration levels.
(4)Coluracetam has also been shown to have stimulant effects. If you suffer from dreariness in the morning, taking this nootropic could help increase energy levels so that you're able to approach the day with improved motivation. This will help you complete tasks, maintaining an edge in the workplace.
DOSING
Since the study subjects were mainly rats, there isn't any
recommended human dosages, but there is a general guideline for
conversion.
In rats, the dosage ranged between 1 mg/kg and 10 mg/kg per day. By
using allometric scaling, the dose becomes 2.9 mg/kg in humans, so
the average dose should not exceed 203.5 mg daily for someone in a
typical weight class.
There isn't very much information to indicate toxicity of
Coluracetam, although doses given at the above increments showed no
negative side effects. If you haven't used a nootropic before, you
may develop headache after use, which is a common in first time
users. By stacking the Coluracetam with Choline, you'll reduce this
risk.
Application
Memory and Learning
Coluracetam is shown to improve cognitive function and memory in
rats, and in theory, the same results are expected in human beings.
A study conducted by BrainCells Inc, showed a memory improvement in
rats who were given substance AF64A (a neuron-specific neurotoxin)
for 8 days along with Coluracetam in 3mg doses. These rats were put
through the standardized Morris Water Maze to mark their ability to
get through it, and even up to 72 hours after the last 8mg dose,
they were still able to. Another key finding of this study was that
the results were still apparent 3 days after the last dose, even
though the serum concentration of Coluracetam was negligible.
Depression and Anxiety
BrainCells Inc, found that a dosage of 240mg (split into three
daily doses of 80mg) was useful in treating major depression
co-morbid with GAD (generalized anxiety disorder). However, the
differences were most pronounced in those who didn't find relief in
using standard antidepressants. After one dose, there were no
noticeable differences, but after 2 doses at 80mg, 36% had improved
scores during a depression assessment test.
Eyesight
Coluracetam has been associated with optic benefits such as
enhanced color vision, recognition and vividness. Although there
isn't any conclusive evidence to support the mechanisms behind this
benefit, experts believe that Coluracetam works in the part of the
brain that runs visual processes.
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